AP 14145 hydrochloride

AP 14145 hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  AP 14145 hydrochloride is a KCa2 (small conductance Ca2+-activated potassium) channel negative allosteric modulator (IC50 = 1.1 μM). Increases the EC50 of Ca2+ on KCa2.3 channels by ~3-fold. Prolongs atrial effective refractory period (AERP) in rats. Reduces atrial fibrillation (AF) duration and prolongs atrial refractoriness without affecting ventricular refractory period in an animal AF model.

• Lager

  Store at -20°C

AP 14145 hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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