2-Pyridinecarboxamide, N-[3-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl]amino]propyl]-N-[4-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl][3-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl][2-(4-isothiocyanatophenyl)ethyl]amino]propyl]amino]butyl]-1,6-dihydro-1-hydroxy-6-oxo-

2-Pyridinecarboxamide, N-[3-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl]amino]propyl]-N-[4-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl][3-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl][2-(4-isothiocyanatophenyl)ethyl]amino]propyl]amino]butyl]-1,6-dihydro-1-hydroxy-6-oxo- Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  p-SCN-Bn-HOPO is a superior bifunctional chelator for (89)Zr ImmunoPET. In vivo studies demonstrate the successful use of (89)Zr-HOPO-trastuzumab to image BT474 breast cancer with low background, good tumor to organ contrast, and, importantly, very low bone uptake. The reduced bone uptake seen with (89)Zr-HOPO-trastuzumab suggests superior stability of the (89)Zr-HOPO complex.

2-Pyridinecarboxamide, N-[3-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl]amino]propyl]-N-[4-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl][3-[[(1,6-dihydro-1-hydroxy-6-oxo-2-pyridinyl)carbonyl][2-(4-isothiocyanatophenyl)ethyl]amino]propyl]amino]butyl]-1,6-dihydro-1-hydroxy-6-oxo- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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