4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  The empirical formula of this alkaloid should read C9H II N 504' The natural compound is the D-Erythro-form of the base. Melting points recorded for this alkaloid are 279°C (dec.) by Kamiya et al and 26l-3°C (dec.) by Chibata and his colleagues. The alkaloid has specific rotations of [α]_D+ 16° (N-HC1) and [α] _D + 50° (0.1 N-NaOH). It gives an ultraviolet spectrum in H20 with a single absorption maximum at 26l.5 nm which is shifted to 259.5 nm inN-HCl and is at 262 nm in N-NaOH. Eritadenine forms a methyl ester, m.p. 231°C (dec.) and a diacetate, m.p. 225°C (dec.).

• Chemische Eigenschaften

  Pale Yellow Solid

• Verwenden

  Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.

• Einzelnachweise

  Chibata et al., Experientia, 25,1237 (1969)
  Kamiya et al., Tetrahedron Lett., 4729 (1969)

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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