BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

• Synthese

  
  To a solution of thioanilide 7 (2 mmol) dissolved by gentle warming at 40 °C and then cooled to 0 °C in glacial acetic acid (diluted with 5% water, 15 mL) was added NaNO2 (0.21 g, 3 mmol) in portions over 5 min with stirring. After 30 min, ice water (～100 mL) was added, and the precipitated product was filtered and washed with water. The orange solid was dried in vacuo at rt overnight and then at 50 °C for 4 h to afford benzotriazoles 1-(N-BOC-L-thionophenylalaninyl)-6-nitrobenzotriazole (9b): yield 81%. as amorphous solids of sufficient purity for use in the next step.

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Upstream-Materialien And Downstream Produkte

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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