Natriumbenzoat Produkt Beschreibung
- Englisch Name:Sodium benzoate
- Synonyma:Natriumbenzoat;Benzoesäure, Natriumsalz
ucephan;PUROX S;antimol;sobenate;FEMA 3025;BENZOTRON;BENZOTRON(R);benzoansodny;femanumber3025;NATRII BENZOAS
Natriumbenzoat physikalisch-chemischer Eigenschaften
- Schmelzpunkt: :>300 °C(lit.)
- Dichte :1,44 g/cm3
- FEMA :3025 | SODIUM BENZOATE
- Flammpunkt: :>100°C
- storage temp. :Store at RT.
- Löslichkeit :H2O: 1 M at 20 °C, clear, colorless
- Aggregatzustand :Crystals, Granules, Flakes or Crystalline Powder
- Farbe :White
- PH :7.0-8.5 (25℃, 1M in H2O)
- Wasserlöslichkeit :soluble
- Merck :14,8582
- BRN :3572467
- Stabilität: :Stable, but may be moisture senstive. Incompatible with strong oxidizing agents, alkalis, mineral acids.
- InChIKey :WXMKPNITSTVMEF-UHFFFAOYSA-M
- CAS Datenbank :532-32-1(CAS DataBase Reference)
- NIST chemische Informationen :Sodium benzoate(532-32-1)
- EPA chemische Informationen :Benzoic acid, sodium salt(532-32-1)
Sodium benzoate Chemische Eigenschaften,Einsatz,Produktion Methoden
- ERSCHEINUNGSBILD WEISSES HYGROSKOPISCHES KRISTALLINES PULVER ODER GRANULAT.
- PHYSIKALISCHE GEFAHREN Staubexplosion der pulverisierten oder granulierten Substanz in Gemischen mit Luft möglich.
- CHEMISCHE GEFAHREN Zersetzung beim Erhitzen unter Bildung reizender Rauche.
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
- INHALATIONSGEFAHREN Eine belästigende Partikelkonzentration in der Luft kann beim Dispergieren schnell erreicht werden, besonders als Pulver.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt leicht die Augen.
- LECKAGE Persönliche Schutzausrüstung: Atemschutzgerät, P1-Filter für inerte Partikel. Verschüttetes Material in abgedeckten Behältern sammeln.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R62:Kann möglicherweise die Fortpflanzungsfähigkeit beeinträchtigen.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R68:Irreversibler Schaden möglich.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
- Beschreibung Sodium benzoate has the chemical formula NaC7H5O2; it is a widely used food preservative, with E number E211. It is the sodium salt of benzoic acid and exists in this form when dissolved in water. It can be produced by reacting sodium hydroxide with benzoic acid.
- Chemische Eigenschaften Sodium benzoate is a white crystalline solid. It is odorless and nonflammable
- Chemische Eigenschaften Sodium benzoate occurs as a white granular or crystalline, slightly hygroscopic powder. It is odorless, or with faint odor of benzoin and has an unpleasant sweet and saline taste.
- Chemische Eigenschaften white crystalline powder
- Chemische Eigenschaften Benzoic acid is almost odorless or exhibits a sweet, faint, balsamic odor and a sweet–sour to acrid taste. For a detailed description, refer to Burdock (1997).
- Occurrence Benzoic acid occurs naturally in many plants and in animals. The salt is not found to occur naturally.
- Verwenden Vasodilator
- Verwenden A benzene compound used as a synthetic reagent.
- Verwenden Antimicrobial agent, flavoring agent and adjuvant in food; not to exceed a maximum level of 0.1% in food (21 CFR, 184.1733, 582.3733). Antifungal and bacteriostatic preservative in pharmaceuticals at concentrations of ~0.1%. Clinical reagent (bilirubin assay).
- Verwenden sodium benzoate is a non-toxic, organic salt preservative that is particularly effective against yeast, with some activity against molds and bacteria. It is generally used in concentrations of 0.1 to 0.2 percent.
- Verwenden Sodium Benzoate is a preservative that is the sodium salt of benzoic acid. it converts to benzoic acid, which is the active form. it has a solubility in water of 50 g in 100 ml at 25°c. sodium benzoate is 180 times as soluble in water at 25°c as is the parent acid. the optimum functionality occurs between ph 2.5 and 4.0 and it is not recom- mended above ph 4.5. it is active against yeasts and bacteria. it is used in acidic foods such as fruit juices, jams, relishes, and bever- ages. its use level ranges from 0.03 to 0.10%.
Sodium benzoate is a preservative. It is bacteriostatic and fungistatic under acidic conditions. It is most widely used in acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments. It is also used as a preservative in medicines and cosmetics. As a food additive, sodium benzoate has the E number E211.
It is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited. The fuel is also one of the fastest burning rocket fuels and provides a lot of thrust and smoke. It does have its downsides: there is a high danger of explosion when the fuel is sharply compressed because of the fuel's sensitivity to impact.
- Vorbereitung Methode Sodium benzoate is prepared by adding benzoic acid to a hot concentrated solution of sodium carbonate until effervescence ceases. The solution is then evaporated, cooled and allowed to crystallize or evaporate to dryness, and then granulated.
- Vorbereitung Methode Prepared by the treatment of benzoic acid with either sodium carbonate or sodium bicarbonate.
- Definition sodium benzoate: An either colourlesscrystalline or white amorphouspowder, C6H5COONa, soluble inwater and slightly soluble in ethanol.It is made by the reaction of sodiumhydroxide with benzoic acid and isused in the dyestuffs industry and asa food preservative. It was formerlyused as an antiseptic.
- Definition ChEBI: An organic sodium salt resulting from the replacement of the proton from the carboxy group of benzoic acid by a sodium ion.
- synthetische Produced by the neutralization of benzoic acid with sodium bicarbonate, sodium carbonate or sodium hydroxide.
- Hazard Use in foods limited to 0.1%.
Sodium benzoate is used primarily as an antimicrobial preservative
in cosmetics, foods, and pharmaceuticals. It is used in concentrations
of 0.02–0.5% in oral medicines, 0.5% in parenteral products,
and 0.1–0.5% in cosmetics. The usefulness of sodium benzoate as a
preservative is limited by its effectiveness over a narrow pH range.
Sodium benzoate is used in preference to benzoic acid in some circumstances, owing to its greater solubility. However, in some applications it may impart an unpleasant flavor to a product. Sodium benzoate has also been used as a tablet lubricant at 2–5% w/w concentrations. Solutions of sodium benzoate have also been administered, orally or intravenously, in order to determine liver function.
- Sicherheitsprofil Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion, intramuscular, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Larger doses of 8-10 g by mouth may cause nausea and vomiting. Small doses have little or no effect. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Na2O. See also BENZOIC ACID.
Ingested sodium benzoate is conjugated with glycine in the liver to
yield hippuric acid, which is excreted in the urine. Symptoms of systemic benzoate toxicity resemble those of salicylates. Whereas
oral administration of the free-acid form may cause severe gastric
irritation, benzoate salts are well tolerated in large quantities: e.g. 6
g of sodium benzoate in 200mL of water is administered orally as a
liver function test.
Clinical data have indicated that sodium benzoate can produce nonimmunological contact urtcaria and nonimmunological immediate contact reactions. However, it is also recognized that these reactions are strictly cutaneous, and sodium benzoate can therefore be used safely at concentrations up to 5%. However, this nonimmunological phenomenon should be considered when designing formulations for infants and children.
Other adverse effects include anaphylaxis and urticarial reactions, although a controlled study has shown that the incidence of urticaria in patients given benzoic acid is no greater than that with a lactose placebo.
It has been recommended that caffeine and sodium benzoate injection should not be used in neonates; however, sodium benzoate has been used by others in the treatment of some neonatal metabolic disorders. It has been suggested that there is a general adverse effect of benzoate preservatives on the behavior of 3-yearold children, which is detectable by parents, but not by a simple clinical assessment.
The WHO acceptable daily intake of total benzoates, calculated as benzoic acid, has been estimated at up to 5 mg/kg of bodyweight.
LD50 (mouse, IM): 2.3 g/kg
LD50 (mouse, IV): 1.4 g/kg
LD50 (mouse, oral): 1.6 g/kg
LD50 (rabbit, oral): 2.0 g/kg
LD50 (rat, IV): 1.7 mg/kg
LD50 (rat, oral): 4.1 g/kg
- Sicherheit(Safety) In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate form benzene, a known carcinogen. However, in most beverages that contain both, the benzene levels are below those considered dangerous for consumption. Heat, light and shelf life can affect the rate at which benzene is formed.
- mögliche Exposition Sodium benzoate is used as a food and feed additive, flavor, packaging material; pharmaceutical; preservative for food products and tobacco; anti-fungal agent; antiseptic, rust, and mildew inhibitor; intermediate in the manufacture of dyes. Used as a human hygiene biocidal product.
- Lager Aqueous solutions may be sterilized by autoclaving or filtration. The bulk material should be stored in a well-closed container, in a cool, dry place.
- Versand/Shipping UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
- läuterung methode Crystallise it from EtOH (12mL/g). [Beilstein 9 IV 27.]
- Mechanism of food preservation The mechanism starts with the absorption of benzoic acid into the cell. If the intracellular pH changes to 5 or lower, the anaerobic fermentation of glucose through phosphofructokinase is decreased by 95 %, thereby inhibiting the growth and survival of micro-organisms that cause food spoilage.
- Inkompatibilitäten Incompatible with quaternary compounds, gelatin, ferric salts, calcium salts, and salts of heavy metals, including silver, lead, and mercury. Preservative activity may be reduced by interactions with kaolin or nonionic surfactants.
- Inkompatibilitäten Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
- Regulatory Status GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (dental preparations; IM and IV injections; oral capsules, solutions and tablets; rectal; and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium benzoate Upstream-Materialien And Downstream Produkte
- Edge Rate：91
532-32-1, Sodium benzoate Verwandte Suche:
- Benzoesure Zitronensure Natriumsalicylat 2-(4,5-Dibrom-3,6-dihydroxy-2,7-dinitroxanthen-9-yl)-benzoesure, dinatriumsalz Trinatrium-5-[(3-carboxylato-5-methyl-4-oxo-2,5-cyclohexadien-1-yliden)(2,6-dichlor-3-sulfonatophenyl)methyl]-2-hydroxy-3-methylbenzoat Natrium-hydrogen-4-chlorphthalat sodium 2,2-Dimethoxy-1,2-diphenylethan-1-on Gummi benzoin, Siam- Denatoniumbenzoat Natriumbenzoat (±)-2-Hydroxy-1,2-diphenylethan-1-on Sodium alginate 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Trinatriumorthophosphat BENZOICACID Emamectin benzoate Trinatriumcitrat
- Soudium benzoate
- BENZOIC ACID SODIUM SALT
- FEMA 3025
- SODIUM BENZOATE
- PUROX S
- benzoic acid sodium crystalline
- benzoic acid sodium sigmaultra
- SODIUM BENZOATE BP 93
- Sodium benzoate Food grad
- SODIUM BENZOATE, REAGENTPLUS, 99%
- Sodium benzoate,Benzoic acid sodium salt
- Sodium benzoate, synthesis grade
- Sodium Benzoate (1 g)
- Cactus Plant Extract
- SodiuM Benzoate [for BiocheMical Research]
- SodiuM Benzoate Powder / Granule
- Sodium Benzoate, fine powder
- SodiuM Benzoate, Technical
- SodiuM benzoate, 99%, for biocheMistry
- SodiuM benzoate, 99+%, extra pure
- Sodium Benzonate
- Sodium benzoate puriss., meets analytical specification of Ph.Eur., BP, FCC, E211, 99.0-100.5% (calc. to the dried substance), powder
- Sodium benzoate purum p.a., >=99.0% (NT)
- Sodium benzoate ReagentPlus(R), 99%
- Sodium benzoate Vetec(TM) reagent grade, 98%
- CYTIDINE-5'-TRIPHOSPHATE 3NA ULTRA PURE
- POTASSIUM SODIUM L(+)-TARTRATE 4H2O GPR
- SODIUM BENZOATE, BIOXTRA, >=99.5%
- NATRII BENZOAS
- Sodium benzoate Manufacturer
- SODIUM BENZOATE, REAGENTSODIUM BENZOATE, REAGENTSODIUM BENZOATE, REAGENTSODIUM BENZOATE, REAGENT
- SODIUM BENZOATE, 1GM, NEAT
- SODIUM BENZOATE, PH EUR
- SODIUM BENZOATE POWDER, EXTRA PURE, DAB, B. P., FCC, E 211
- SODIUM BENZOATE 99+% FCC