ANTI-CLUSTERIN, HUMAN

ANTI-CLUSTERIN, HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-Clusterin antibody produced in rabbit has been used in immunohistochemical (IHC) staining (1:1,000 & 1:100).

• Biologische Aktivität

  Clusterin (CLU) is a multifunctional plasma protein and a fluid-phase complement inhibitor. It mediates the complement terminal pathway. Clusterin is an ATP-independent small he at shock protein-like chaperone. It functions as a redox sensor and a lipid transporter. Clusterin is associated with many age-related diseases such as neurodegeneration and metabolic syndrome. It is involved in cancer progression, promotion, metastasis, and chemoresistance. Increased serum CLU levels are observed in type 2 diabetes (T2D). It is known to suppress proteotoxicity. Clusterin might show anti or proapoptotic activities. This protein is associated with different functions of the brain. A single nucleotide polymorphism (SNP) in the CLU gene might cause the development of late-onset Alzheimerμs disease (LOAD).

ANTI-CLUSTERIN, HUMAN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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