DI-8-ANEPPS Struktur

DI-8-ANEPPS

Bezeichnung:DI-8-ANEPPS

CAS-Nr157134-53-7

Englisch Name:DI-8-ANEPPS

CBNumberCB0670762

SummenformelC36H52N2O3S

Molgewicht592.87

MOL-Datei157134-53-7.mol

DI-8-ANEPPS physikalisch-chemischer Eigenschaften

Schmelzpunkt	>200℃
storage temp.	2-8°C
Löslichkeit	DMSO: soluble
Aggregatzustand	powder
Farbe	orange to red
maximale Wellenlänge (λmax)	498 nm
Biologische Anwendungen	Measuring membrane potential

Sicherheit

WGK Germany

DI-8-ANEPPS Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.
Verwenden
Di-8-ANEPPS is a fast-responding membrane potential dye. It is more suitable for long-term membrane potential studies than di-4-ANEPPS (sc-214872) because of its better retention in the outer leaflet of plasma membranes. This dye is weakly fluorescent in aqueous media, and becomes strongly fluorescent upon binding to lipophilic environments (such as membranes). Di-8-ANEPPS is less susceptible for cellular internalization due to the sulfonate group it possesses.Dyes and metabolites.
Verwenden
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.

DI-8-ANEPPS Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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