SALVINORIN A

Bezeichnung:SALVINORIN A

CAS-Nr83729-01-5

Englisch Name:SALVINORIN A

CBNumberCB0506991

SummenformelC23H28O8

Molgewicht432.46

MOL-Datei83729-01-5.mol

SALVINORIN A physikalisch-chemischer Eigenschaften

Schmelzpunkt	238-240° (Ortega); mp 242-244° (Valdes, 1984)
alpha	D22 -45.3° (c = 8.530 in CHCl3); D25 -41° (c = 1 in CHCl3)
Siedepunkt	563.8±50.0 °C(Predicted)
Dichte	1.28±0.1 g/cm3(Predicted)
Flammpunkt	2℃
storage temp.	−20°C
Löslichkeit	DMSO: ≥10mg/mL
Aggregatzustand	powder
Farbe	white

Sicherheit

Kennzeichnung gefährlicher	F,Xn
R-Sätze:	11-20/21/22-36
S-Sätze:	22-24/25-36/37-16
RIDADR	UN 1648 3 / PGII
WGK Germany	3
RTECS-Nr.	QL6127142
Giftige Stoffe Daten	83729-01-5(Hazardous Substances Data)

Gefahreninformationscode (GHS)

SALVINORIN A Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Salvinorin A (Item No. 11487) is an analytical reference material categorized as a diterpene. It is a hallucinogen derived from S. divinorum that has been used in the traditional spiritual practices of the Mazatec Indians and as a recreational drug. This product is intended for research and forensic applications.
Verwenden
Salvinorin A is a hallucinogenic derived from the S. divinorum plant used in traditional spiritual practices of the Mazatec Indians and now gaining popularity as a recreational drug. Unlike other hallucinogens, which mediate their effects through serotonin 5-HT2A receptors, salvinorin A is a potent, selective κ-opioid receptor agonist (Ki = 2.4 nM; EC50 = 1.8 nM). This product is intended for forensic and research applications.In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.
Verwenden
In traditional medicine, the leaves are used for divination and for treatment of anemia and excretory functions.
Verwenden
Salvinorin A is a potent and selective kappa-opioid receptor agonist. Salvinorin A has been reported to be brain-penetrant and displays psychoactive properties; hallucinogen.
Definition
ChEBI: A natural product found in Salvia divinorum.
Biologische Aktivität
Potent naturally occuring non-nitrogenous κ -opioid selective agonist that displays high affinity at both native (K i = 4.3 nM) and cloned (K i = 16 nM) κ -opioid receptors. Also exhibits allosteric modulation of μ -opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties.
Biochem/physiol Actions
Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

SALVINORIN A Upstream-Materialien And Downstream Produkte

SALVINORIN A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

83729-01-5, SALVINORIN A Verwandte Suche:

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