1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  This alkaloid has recently been shown to exhibit a marked antineoplastic activity. Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until death to mice which had been inoculated with a single intraperitoneal dose of 106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent compared with control animals.
  Japanese workers have recently reported the synthesis of olivacine by heating indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per cent HBr.

• Definition

  ChEBI: Olivacine is a member of carbazoles.

• Synthesis Reference(s)

  Journal of Heterocyclic Chemistry, 27, p. 1751, 1990 DOI: 10.1002/jhet.5570270645

• Einzelnachweise

  Regina et al., Cienc. Cult. (Sao Paulo), 26, 517 (1974)
  Synthesis: Kametani et al., J. Chern. Soc., Perkin I, 2102 (1975)

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Upstream-Materialien And Downstream Produkte

1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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