ANTI-SYNAPTOPHYSIN

ANTI-SYNAPTOPHYSIN Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Monoclonal Anti-Synaptophysin antibody has been used in western blotting.

• Verwenden

  Anti-Synaptophysin antibody produced in rabbit has been used in:
  
  • immunocytochemistry
  • western blotting
  • immunohistochemistry

• Allgemeine Beschreibung

  Synaptophysin (SYP) is an integral membrane glycoprotein of 38,000 Da and it has four membrane-spanning domains. Synaptophysin is localized to neurons, neuromuscular junctions, paraganglia cells, hypophysis, pancreatic islet cells, and adrenal cells. SYP gene is mapped to human chromosome Xp11.23. Monoclonal Anti-Synaptophysin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

• Biochem/physiol Actions

  Synaptophysin (SYP) modulates neurotransmitter release and synaptic plasticity. It maintains biogenesis and recycling of synaptic vesicles. SYP functions as a marker for neuroendocrine tumors. It is used as a potent marker for neuroendocrine prostate cancer (NEPC). Mutations in this gene is associated with X-linked intellectual disability.

ANTI-SYNAPTOPHYSIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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