Uridine

Bezeichnung:Uridine

CAS-Nr58-96-8

Englisch Name:Uridine

CBNumberCB0330400

SummenformelC9H12N2O6

Molgewicht244.2

MOL-Datei58-96-8.mol

Uridine physikalisch-chemischer Eigenschaften

Schmelzpunkt	163-167 °C(lit.)
alpha	8.4 º (c=2,water)
Siedepunkt	387.12°C (rough estimate)
Dichte	1.4221 (rough estimate)
Brechungsindex	9 ° (C=2, H2O)
storage temp.	2-8°C
Löslichkeit	H₂O: 50 mg/mL
Aggregatzustand	powder
pka	9.39±0.10(Predicted)
Farbe	White to almost white
Wasserlöslichkeit	Soluble in water, dimethylsulfoxide, and methanol.
Merck	14,9877
BRN	754904
InChIKey	DRTQHJPVMGBUCF-XVFCMESISA-N
LogP	-1.581 (est)
CAS Datenbank	58-96-8(CAS DataBase Reference)
NIST chemische Informationen	Uridine(58-96-8)
EPA chemische Informationen	Uridine (58-96-8)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	24/25-36-26
WGK Germany	3
RTECS-Nr.	YR1450000
F	10
Hazard Note	Keep Cold
TSCA	Yes
HS Code	29335990

Gefahreninformationscode (GHS)

Uridine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White powder; odorless; slightly acrid and faintly sweet taste. Soluble in water; slightly soluble in dilute alcohol; insoluble in strong alcohol.
Verwenden
Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond
Verwenden
Uridine is a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)
Definition
ChEBI: Uridine is a ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a beta-N(1)-glycosidic bond. It has a role as a human metabolite, a fundamental metabolite and a drug metabolite. It is functionally related to a uracil.
Allgemeine Beschreibung
Uridine is a pyrimidine nucleoside which is crucial for the synthesis of RNA and membranes. It helps in normal cell function and growth by forming pyrimidine nucleotide -lipid conjugates. Uridine has been studied as a rescue agent to reduce the toxicities associated with 5-fluorouracil (5-FU), thereby allowing the administration of higher doses of 5-FU in chemotherapy regimens. (NCI04)
Biochem/physiol Actions
Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.
target
ATPase | Potassium Channel | p53
läuterung methode
Crystallise -uridine from aqueous 75% MeOH or EtOH (m 165-166o). [Beilstein 24 III/IV 1202.]

Uridine Upstream-Materialien And Downstream Produkte

Uridine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

58-96-8, Uridine Verwandte Suche:

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