7,8-DIHYDRO-L-BIOPTERIN Struktur

7,8-DIHYDRO-L-BIOPTERIN

Bezeichnung:7,8-DIHYDRO-L-BIOPTERIN

CAS-Nr6779-87-9

Englisch Name:7,8-DIHYDRO-L-BIOPTERIN

CBNumberCB0320957

SummenformelC9H13N5O3

Molgewicht239.23

MOL-Datei6779-87-9.mol

7,8-DIHYDRO-L-BIOPTERIN physikalisch-chemischer Eigenschaften

Schmelzpunkt	>300°C dec.
Siedepunkt	470.8±55.0 °C(Predicted)
Dichte	1.88
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Löslichkeit	Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly), DMSO (Slightly)
Aggregatzustand	Solid
pka	10.47±0.20(Predicted)
Farbe	Pale Yellow to Brown
BRN	536551
Stabilität	Hygroscopic
InChIKey	FEMXZDUTFRTWPE-AWFVSMACSA-N
CAS Datenbank	6779-87-9

Sicherheit

WGK Germany	3
F	3-10

Gefahreninformationscode (GHS)

7,8-DIHYDRO-L-BIOPTERIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
BH₂ is a precursor of BH₄ synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a K_i of 14.4 μM.
Chemische Eigenschaften
Yellow Powder
Verwenden
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Verwenden
An oxidation producct of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of G
Verwenden
The reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Definition
ChEBI: L-erythro-7,8-dihydrobiopterin is a 7,8-dihydrobiopterin in which the 1,2-dihydroxypropyl group has (1R,2S)-configuration; naturally occurring form. It is an enantiomer of a D-erythro-7,8-dihydrobiopterin.
Einzelnachweise
[1] shen r, alam a, zhang y. inhibition of gtp cyclohydrolase i by pterins[j]. biochimica et biophysica acta (bba)-general subjects, 1988, 965(1): 9-15.
[2] sugiyama t, levy b d, michel t. tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells[j]. journal of biological chemistry, 2009, 284(19): 12691-12700.

7,8-DIHYDRO-L-BIOPTERIN Upstream-Materialien And Downstream Produkte

7,8-DIHYDRO-L-BIOPTERIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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