4-Ethylresorcin

Bezeichnung:4-Ethylresorcin

CAS-Nr2896-60-8

Englisch Name:4-Ethylresorcinol

CBNumberCB0300724

SummenformelC8H10O2

Molgewicht138.16

MOL-Datei2896-60-8.mol

Synonyma

4-Ethylresorcin

4-Ethylresorcin physikalisch-chemischer Eigenschaften

Schmelzpunkt	95-98 °C (lit.)
Siedepunkt	155 °C / 10mmHg
Dichte	1.0742 (rough estimate)
Brechungsindex	1.5231 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Solubility in methanol; almost transparency. Soluble in alcohol.
Aggregatzustand	Crystalline Powder
pka	10.06±0.10(Predicted)
Farbe	Slightly beige
BRN	1238231
InChIKey	VGMJYYDKPUPTID-UHFFFAOYSA-N
LogP	1.731 (est)
CAS Datenbank	2896-60-8(CAS DataBase Reference)
NIST chemische Informationen	1,3-Benzenediol, 4-ethyl-(2896-60-8)
EPA chemische Informationen	4-Ethylresorcinol (2896-60-8)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-37/39-36
WGK Germany	3
TSCA	Yes
HS Code	29072100

Gefahreninformationscode (GHS)

4-Ethylresorcinol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol has hypopigmentation effects.4-Ethylresorcinol attenuates the mRNA and protein expression of tyrosinase-related protein (TRP)-2, and has an antioxidant effect through the inhibition of lipid peroxidation. 4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol is a derivative of resorcinol.
Chemische Eigenschaften
slightly beige crystalline powder
Verwenden
It is employed as an active pharmaceutical intermediate.
Definition
ChEBI: 4-Ethylresorcinol is a member of resorcinols.
Synthesis Reference(s)
Synthetic Communications, 15, p. 1315, 1985 DOI: 10.1080/00397918508077280
Synthese
The synthesis of 4-Ethylresorcinol is as follows:
In a three necked round bottom flask (equipped with a condensor, additional funnel and mechanical stirrer) was added 15.2 g of a combination of Raney Nickel and Ni supported on silica. (50: 50). 100 ml of a mixture of 50: 50 ethanol: water was added and the reaction was heated at reflux conditions. 15.2 g of 2,4-dihydroxy acetophenone in 100 ml of water: ethanol and 10 ml of acetic acid was placed in the additional funnel and slowly added to the mixture (dropwise). The reaction was filtered through a milipore filter to give a pale yellow solution. Concentration of this solution in vacuo gave a solid. This solid was crystalized from 1,2-dichloroethane to give 4-ethyl resorcinol in 80% isolated yield.

4-Ethylresorcinol Upstream-Materialien And Downstream Produkte

4-Ethylresorcin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2896-60-8, 4-Ethylresorcinol Verwandte Suche:

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