Monoclonal Anti-HLA Class I Antigen

Monoclonal Anti-HLA Class I Antigen Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
  Immunofluorescence (1 paper)

• Verwenden

  FITC Monoclonal Anti-Human HLA Class I Antigen may be used for immunochemical analysis of HLA Class I antigens; Studies of HLA-A,B,C expression on embryonic and neoplastic tissues; and/or the purification of HLA-A,B,C antigens.

• Allgemeine Beschreibung

  Monoclonal Anti-Human HLA Class I Antigen (mouse IgG2a isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cell line NS-1 and splenocytes from BALB/c mice immunized with human tonsil leukocyte membrane preparation. Class I proteins are highly polymorphic. HLA-A, -B, -C are classical class I proteins and are heterodimers. HLA-A consists of a polymorphic transmembrane α heavy chain and an invariant water-soluble light chain.

• Biochem/physiol Actions

  HLA class I molecules like HLA-A,?-B and ?C help in the presentation of endogenous antigen to CD8+ (cluster of differentiation 8) T cells.

Monoclonal Anti-HLA Class I Antigen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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