Diminutol

Diminutol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (K_i = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.

• Verwenden

  Diminutol is a cell-permeable purine analog that inhibits NQ01 and blocks mitotic spindle assembly.

• Verwenden

  Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.[Cayman Chemical]

Diminutol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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