Sulfacetamide sodium

Bezeichnung:Sulfacetamide sodium

CAS-Nr6209-17-2

Englisch Name:Sulfacetamide sodium

CBNumberCB0268507

SummenformelC8H13N2NaO4S

Molgewicht256.25

MOL-Datei6209-17-2.mol

Sulfacetamide sodium physikalisch-chemischer Eigenschaften

Schmelzpunkt	263-265°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	H2O: soluble50mg/mL
Aggregatzustand	powder
Farbe	white to off-white
Wasserlöslichkeit	Freely soluble in water. Insoluble in chloroform, ether, and benzene.
CAS Datenbank	6209-17-2

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37
WGK Germany	3
RTECS-Nr.	AC8480000
HS Code	29350090

Gefahreninformationscode (GHS)

Sulfacetamide sodium Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White or yellowish-white, crystalline powder.
Verwenden
Antibacterial;Inhibitor of folic acid synthesis
Verwenden
Sulfacetamide sodium salt hydrate is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections. It adapts to cure trachoma, conjunctivitis, keratitis.
Definition
ChEBI: Sulfacetamide sodium is an organic sodium salt that is the monohydrate form of sulfacetamide sodium. It has a role as an antimicrobial agent, an antiinfective agent and an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. It is an organic sodium salt and a hydrate. It contains a member of sulfacetamide sodium anhydrous.
Allgemeine Beschreibung
N-Sulfanilylacetamide monosodium salt (Sodium Sulamyd)is obtained as the monohydrate and is a white, odorless, bitter,crystalline powder that is very soluble (1:2.5) in water.Because the sodium salt is highly soluble at the physiologicalpH of 7.4, it is especially suited, as a solution, forrepeated topical applications in the local management ofophthalmic infections susceptible to sulfonamide therapy.
Biochem/physiol Actions
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Sulfacetamide sodium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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