OlMesartan MedoxoMil-d6

OlMesartan MedoxoMil-d6 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Olmesartan medoxomil-d₆ is intended for use as an internal standard for the quantification of olmesartan medoxomil by GC- or LC-MS. Olmesartan medoxomil is an orally bioavailable prodrug form of olmesartan , a nonpeptide angiotensin II antagonist that is selective for the angiotensin 1 (AT₁) receptor over the AT₂ receptor. Olmesartan medoxomil (0.1 mg/kg) inhibits the angiotensin II pressor response in normotensive rats. It reduces both systolic and diastolic blood pressure in fructose-fed rats, a model of insulin resistance, when administered at a dose of 10 mg/kg per day, as well as in chow-fed control animals when administered at a dose of 11.4 mg/kg per day. Olmesartan medoxomil also inhibits increases in plasma levels of triglycerides and non-esterified fatty acids in fructose-fed rats. Formulations containing olmesartan medoxomil have been used in the treatment of hypertension.

• Chemische Eigenschaften

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• Verwenden

  OlMesartan MedoxoMil-d6 is an angiotensin II receptor antagonist,it is used as an anti-hypertensive.

• Verwenden

  Labelled Olmesartan Medoxomil (O550000). Olmesartan Medoxomil is an angiotensin II receptor antagonist. Olmesartan Medoxomil is used as an anti-hypertensive.

• Verwenden

  A labelled angiotensin II receptor antagonist. Used as an anti-hypertensive.

OlMesartan MedoxoMil-d6 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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