Secretin (Schwein)

Secretin Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Secretin was the first hormone identified. It is a secretagogue of pancreatic digestive juices from the porcine duodenum, used to aid in the diagnosis of gastrinoma. Secretin was discovered by Bayliss and Starling in 1902 as a secretagogue of pancreatic juices from the porcine duodenum. It was the first hormone identified.

• Verwenden

  Stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.

• Trademarks

  SecretinKabi (KabiVitrum, Sweden).

• Allgemeine Beschreibung

  Secretin is a 27-amino-acid polypeptide that is structurallysimilar to glucagon. The presence of acid in the small intestineis the most important physiological stimulus for the secretionof secretin. The primary action of secretin is on pancreatic acinarcells that regulate the secretion of water and bicarbonate.Secretin also promotes the secretion of pancreatic enzymes, toa lesser extent. Secretin inhibits the release of gastrin and,therefore, gastric acid. It also increases stomach-emptyingtime by reducing the contraction of the pyloric sphincter.

• Clinical Use

  Recombinant human secretin (SecreFlo, ChiRhoStim) is approved for use in stimulating gastrin secretion to aid in the diagnosis of gastrinoma.

Secretin (Schwein) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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