2-Methyl-pyrazin

Bezeichnung:2-Methyl-pyrazin

CAS-Nr109-08-0

Englisch Name:2-Methylpyrazine

CBNumberCB0237950

SummenformelC5H6N2

Molgewicht94.11

MOL-Datei109-08-0.mol

Synonyma

2-Methyl-pyrazin

2-Methylpyrazin

2-Methyl-pyrazin physikalisch-chemischer Eigenschaften

Schmelzpunkt	-29 °C (lit.)
Siedepunkt	135 °C/761 mmHg (lit.)
Dichte	1.03 g/mL at 25 °C (lit.)
FEMA	3309 \| 2-METHYLPYRAZINE
Brechungsindex	n20/D 1.504(lit.)
Flammpunkt	122 °F
storage temp.	2-8°C
Löslichkeit	>20.87 mg/mL in EtOH with ultrasonic; >49.9 mg/mL in DMSO;
pka	1.45(at 27℃)
Aggregatzustand	Liquid
Farbe	Clear colorless to slightly yellow
Geruch (Odor)	at 1.00 % in dipropylene glycol. nutty cocoa roasted chocolate peanut green
Geruchsart	nutty
Wasserlöslichkeit	Fully miscible in water.
JECFA Number	761
BRN	105778
InChIKey	CAWHJQAVHZEVTJ-UHFFFAOYSA-N
LogP	0.18
CAS Datenbank	109-08-0(CAS DataBase Reference)
NIST chemische Informationen	Pyrazine, methyl-(109-08-0)
EPA chemische Informationen	Pyrazine, methyl- (109-08-0)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi,F
R-Sätze:	10-22-36/37/38
S-Sätze:	26-36-16
RIDADR	UN 1993 3/PG 3
WGK Germany	3
RTECS-Nr.	UQ3675000
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29339990
Toxizität	mouse,LD50,intraperitoneal,1820mg/kg (1820mg/kg),Toxicology and Applied Pharmacology. Vol. 17, Pg. 244, 1970.

Gefahreninformationscode (GHS)

2-Methylpyrazine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R10:Entzündlich.
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Beschreibung
2-Methylpyrazine has an odor threshold in water variously reported at 60,000 or 105,000 ppb. May be prepared from the corresponding carboxylic acid; by catalytic dehydrogenation of 2-methyl-piperazine; by condensation of methylglyoxal with ethylenediamine.
Chemische Eigenschaften
2-Methylpyrazine has a nutty, cocoa, green, roasted, chocolate, meaty odor.
Chemische Eigenschaften
clear colorless to slightly yellow liquid
Occurrence
Reported found in bakery products, roasted barley, cocoa products, coffee, dairy products, cooked meats, peanuts, filberts, pecans, popcorn, potato chips, rum and whiskey, soy product, roasted filberts, roasted almonds, guava, papaya, asparagus, kohlrabi, baked and fried potato, milk, boiled egg, smoked fish, beer, coffee, sesame seed, rice, sukiyaki, buckwheat, sweet corn, corn tortillas, malt, wort, wild rice, okra, crayfish, clam, squid and maté.
Verwenden
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Verwenden
2-Methylpyrazine is used as flavoring agents in bread fresh bread, butter, chocolate, chocolate cocoa, coffee, meat roasted, nut almond.
synthetische
From corresponding carboxylic acid; by catalytic dehydrogenation of 2-methyl-piperazine; by condensation of methylglyoxal with ethylenediamine
Definition
ChEBI: Methylpyrazine is a member of the class of pyrazines that is pyrazine in which one of the hydrogens is replaced by a methyl group. It is a flavouring agent found in coffee, peanuts and red peppers. It has a role as a flavouring agent, a plant metabolite and a Maillard reaction product.
Aroma threshold values
Detection: 60 ppb to 100 ppm
Taste threshold values
Taste characteristics at 75 ppm: nutty, brown, musty, roasted and astringent
Allgemeine Beschreibung
2-Methylpyrazine is an alkyl-substituted pyrazine used as a key intermediate in the synthesis of pyrazineamide, an anti-tubercular drug.
Sicherheitsprofil
Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. Flammable liquid when exposed to heat, sparks, or flame. Can react with oxidizing materials. To fight fire, use water spray, foam, dry chemical, CO2. When heated to decomposition it emits highly toxic fumes of NOx.
läuterung methode
Purify it via the picrate and distil the free base. The picrate has m133-134o(from EtOH). [Wiggins & Wise J Chem Soc 4780 1956, Beilstein 23 III/IV 911, 23/5 V 386.]

2-Methylpyrazine Upstream-Materialien And Downstream Produkte

2-Methyl-pyrazin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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