5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinon

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

Metaxalone Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White Crystalline Solid

• Originator

  Skelaxin,Robins,US,1962

• Verwenden

  For the treatment of painful peripheral musculoskeletal conditions and spasticity from upper motor neuron syndromes.

• Verwenden

  muscle relaxant (skeletal)

• Verwenden

  It is a muscle relaxant used to relax muscles and relieve pain

• Verwenden

  Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions. It is commonly used in combination with analgesics to address low back pain. The molecular or cellular actions of metaxalone is not known.[Cayman Chemical]

• Definition

  ChEBI: Metaxalone is an aromatic ether.

• Manufacturing Process

  Urea (118 g, 1.96 mols) was added to 192 g (0.98 mol) of 3-(3',5'- dimethylphenoxy)-1,2-propane-diol which had previously been heated to 150°C. The reaction mixture was then heated rapidly to 195° to 200°C and maintained at this temperature for 5 hours with constant stirring. The resulting mixture was partitioned between water and ethyl acetate and the ethyl acetate layer was dried over sodium sulfate and concentrated. The residue was distilled in vacuo and the fraction boiling at 220° to 225°C/1.5 mm was collected. Yield, 172 g (79%). The distillate was crystallized from dry ethyl acetate; MP, 121.5° to 123°C.

• Therapeutic Function

  Muscle relaxant

Metaxalone Upstream-Materialien And Downstream Produkte

5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(212)Suppliers

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