Butyldi-1-adamantylphosphine

Bezeichnung:Butyldi-1-adamantylphosphine

CAS-Nr321921-71-5

Englisch Name:Butyldi-1-adamantylphosphine

CBNumberCB0165042

SummenformelC24H39P

Molgewicht358.54

MOL-Datei321921-71-5.mol

Butyldi-1-adamantylphosphine physikalisch-chemischer Eigenschaften

Schmelzpunkt	100°C
Siedepunkt	449.6±12.0 °C(Predicted)
storage temp.	Inert atmosphere,Room Temperature
Aggregatzustand	Powder
Farbe	white to yellow
Sensitive	air sensitive
BRN	8726448
InChI	InChI=1S/C24H39P/c1-2-3-4-25(23-11-17-5-18(12-23)7-19(6-17)13-23)24-14-20-8-21(15-24)10-22(9-20)16-24/h17-22H,2-16H2,1H3
InChIKey	HTJWUNNIRKDDIV-UHFFFAOYSA-N
SMILES	P(CCCC)(C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2
CAS Datenbank	321921-71-5

Sicherheit

S-Sätze:	24/25
WGK Germany	3
HS Code	29310095

Gefahreninformationscode (GHS)

Butyldi-1-adamantylphosphine Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Physikalische Eigenschaften
Butyldi-1-adamantylphosphine is a white to yellow solid with a melting point of 100°C and an estimated boiling point of 449.6±12.0°C. Store at room temperature, it is air sensitive.
Verwenden
cataCXium A or di-adamantylalkylphosphine is a bulky and electron-rich phosphine ligand that is highly effective for palladium catalyzed cross-coupling reactions such as Heck and Suzuki coupling, Buchwald-Hartwig amination of aryl chlorides, and α-arylation reactions of ketones.

Other applications:
- palladium-catalyzed carbonylation of aryl and heteroaryl halides
- palladium-catalyzed synthesis of (hetero)aromatic nitriles
- palladium-catalyzed aminocarbonylation of aryl halides
Verwenden
CataCXium A is a catalyst. CataCXium A is an electron-rich phosphine ligand used for palladium catalyzed cross-coupling reactions like Heck and Suzuki coupling reactions.
Verwenden
suzuki reaction
Allgemeine Beschreibung
Sold in collaboration with Solvias AG
Synthese
Phosphonium salt (2.2 mmol) was added to a cooled solution (- 78 ??C) of Et3N (4.44 g, 44 mmol) in di-n-butyl ether (20 mL). The reaction mixture was stirred at -78 ??C for 5 h and then allowed to warm gradually to r.t. The solvent was removed under vacuum and the residue was dissolved in degassed EtOH (5 mL). After stirring for 15 min, the solid was filtered off and dried to yield the desired phosphine, which can be further purified by crystallization from EtOH. Butyldi-1-adamantylphosphine, yield 90%.
31P NMR (C6D6)|?: 24.9. Mp 108-110??C. IR (KBr): 3425 (m, br), 2952 (s), 2847 (s), 2847 (s), 2675 (w), 1446 cm-1 (m). 1H NMR (250 MHz, C6D6): |? = 0.96 (3 H, t, 3JH, H = 7.3 Hz, CH3), 1.35-2.03 (36 H, m, adamantyl-30H, butyl-6H). 13C NMR (62 MHz, C6D6): |? = 41.3 (d, 2JC,P = 11.3 Hz, C-2), 37.4 (C-4), 36.1 (d, 1JC,P = 23.5 Hz, C-1), 33.9 (d, 1JC,P = 26.2 Hz, butyl-|á -CH2), 29.1 (d, 3JC,P = 7.6 Hz, C-3), 24.9 (d, 2JC,P = 13.1 Hz, butyl-|? -CH2), 17.1 (d, 3JC,P = 21.6 Hz, butyl-|? -CH2), 14.3 (butyl-CH3). MS (EI, 70 eV): m/z (%) = 358 (M+, 60), 135 (Ad+, 100).

Butyldi-1-adamantylphosphine Upstream-Materialien And Downstream Produkte

Butyldi-1-adamantylphosphine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

321921-71-5, Butyldi-1-adamantylphosphine Verwandte Suche:

Send Inquriy