Bismut hydroxid nitrat oxid

Bezeichnung:Bismut hydroxid nitrat oxid

CAS-Nr1304-85-4

Englisch Name:Bismuth subnitrate

CBNumberCB0163093

SummenformelBi5H9N4O22

Molgewicht1461.99

MOL-Datei1304-85-4.mol

Synonyma

Bismut hydroxid nitrat oxid

Bismut hydroxid nitrat oxid physikalisch-chemischer Eigenschaften

Schmelzpunkt	260°C
Dichte	4.928
Dampfdruck	0Pa at 20℃
storage temp.	Store at +5°C to +30°C.
Löslichkeit	Practically insoluble in water and in ethanol (96 per cent). It dissolves in mineral acids with decomposition.
Aggregatzustand	Powder/Solid
Farbe	White
PH	3.2 (50g/l, H2O, 20℃)(slurry)
Wasserlöslichkeit	Practically insoluble in water and alcohol. Soluble in dilute HNO{3} and HCl
Sensitive	Hygroscopic
Merck	14,1284
Stabilität	Stability Strong oxidizer - contact with combustible material may lead to fire. Incompatible with reducing agents, organic materials.
CAS Datenbank	1304-85-4(CAS DataBase Reference)
EPA chemische Informationen	Bismuth hydroxide nitrate oxide (Bi5(OH)9(NO3)4O) (1304-85-4)

Sicherheit

Kennzeichnung gefährlicher	O,Xi
R-Sätze:	8-36/37/38
S-Sätze:	17-26-36/37/39-36
RIDADR	UN 1477 5.1/PG 2
WGK Germany	3
RTECS-Nr.	EB2977000
F	8
TSCA	Yes
HS Code	2834 29 80
HazardClass	5.1
PackingGroup	II
Giftige Stoffe Daten	1304-85-4(Hazardous Substances Data)
Toxizität	infant,LDLo,oral,1gm/kg (1000mg/kg),"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 134, 1969.

Gefahreninformationscode (GHS)

Bismuth subnitrate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R8:Feuergefahr bei Berührung mit brennbaren Stoffen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S17:Von brennbaren Stoffen fernhalten.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent. The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.

Bismuth Subnitrate is a basic salt that contains the equivalent of not less than 79.0 percent of bismuth trioxide (Bi2O3),calculated on the dried basis.It is both odorless and tasteless, and is used in bleaching and freckle creams, and hair dyes.
Bismuth subnitrate has been used to induce metallothionein in heart tissue and kidneys and to attenuate the toxicity of Adriamycin and cisplatin compounds, respectively.
Chemische Eigenschaften
White, heavy, Slightly hygroscopic powder
Verwenden
Bismuth subnitrate (BiNO3) is used in the cosmetics industry and to make ceramic and enamel glazes.
Verwenden
It is used pharmaceutically in wound dressing, ointment component and as an antiacid. In cosmetics it is used as a cosmetic white pigment. Used in Ceramic glazes and enamel fluxes.
Verwenden
manufacture of bismuth fluxes for enamels; in cosmetics.
Trademarks
Mammol (Abbott).
Flammability and Explosibility
Non flammable
Pharmakologie
Bismuth subnitrate acts as an antacid that exert protective effects on the gastric mucosa. In a double-blind endoscopically controlled study, bismuth substrate was demonstrated to be effective for symptomatic relief in duodenal ulcers. In the alcohol model of mucosal injury in the rat, bismuth substrate was shown to be cytoprotective. In a randomized clinical study consisting of patients with H. pylori-associated duodenal ulcer, adjunctive use of colloidal bismuth subnitrate in a short treatment regimen with omeprazole and clarithromycin resulted in improved eradication rate of H. pylori.
Mode of action
Based on the findings of a clinical investigation in patients with duodenal ulcer disease and healthy volunteers receiving oral bismuth subnitrate tablets, the protective effects of bismuth subnitrate may be secondary to endogenous mucosal prostaglandin (PGE2) production, which is one of the deficient factors observed in peptic ulcer disease. Antacid neutralizing activity of bismuth subnitrate was demonstrated to have a significant postprandial effect on gastric pH.

Bismut hydroxid nitrat oxid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1304-85-4, Bismuth subnitrate Verwandte Suche:

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