Dimethocaine Hydrochloride Struktur

Dimethocaine Hydrochloride

Bezeichnung:Dimethocaine Hydrochloride

CAS-Nr553-63-9

Englisch Name:Dimethocaine Hydrochloride

CBNumberCB01509593

SummenformelC16H26N2O2.ClH

Molgewicht314.854

MOL-Datei553-63-9.mol

Dimethocaine Hydrochloride physikalisch-chemischer Eigenschaften

Schmelzpunkt	195-196℃
storage temp.	Refrigerator
Löslichkeit	DMSO (Slightly), Water (Slightly)
Aggregatzustand	Solid
Farbe	White to Pale Beige
InChI	InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H
InChIKey	WWTWKTDXBNHESE-UHFFFAOYSA-N
SMILES	C1(=CC=C(N)C=C1)C(=O)OCC(C)(C)CN(CC)CC.Cl

Sicherheit

Toxizität

MLD in mice, rabbits (g/kg): 0.30, 0.15 s.c.; 0.04, 0.015 i.v. (Hirschfelder, Bieter)

Dimethocaine Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Off-White Solid
Verwenden
A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine (C633500).
Verwenden
Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.[Cayman Chemical]
Application
Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson's disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy.
Nebenwirkungen
Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety.

Dimethocaine Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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