Diethyl(methyl)(2-(3-methyl-2-phenylvaleryloxy)ethyl)ammoniumbromid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P304+P340：BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P405：Unter Verschluss aufbewahren.

Valethamate bromide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Murel,Ayerst,US

• Definition

  ChEBI: Valethamate bromide is an alkylbenzene.

• Manufacturing Process

  Benzyl cyanide is first reacted with 2-butylbromide in the presence of sodium amide to give 2-phenyl-3-methylvaleronitrile which is hydrolyzed by sulfuric acid to give 3-methyl-2-phenylpentanoic acid. 24 g of 2-phenyl-3- methylpentanoic acid are heated for one hour at 175° to 185°C with 30 g of 2-diethylaminoethanol and 0.5 g of sodium methylate. The excess diethylaminoethanol is removed in vacuo, the residue is dissolved in 300 cc of 2 N-acetic acid, the acid solution is shaken with ether and made alkaline with concentrated potassium carbonate solution and ice. The ether solution is washed with water, dried with sodium sulfate and evaporated. The residue is distilled under high vacuum, yielding 20 to 21 g of the basic ester (60% of the theoretical) is obtained, the ester boiling at 98° to 100°C at a pressure of 0.03 mm. The hydrochloride of the ester melts at 112°to 113°C and the methobromide at 100° to 101°C.

• Therapeutic Function

  Anticholinergic

• Sicherheitsprofil

  Poison by ingestion, subcutaneous, and intravenous routes. See also ESTERS and BROMIDES. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Br-.

Valethamate bromide Upstream-Materialien And Downstream Produkte

Diethyl(methyl)(2-(3-methyl-2-phenylvaleryloxy)ethyl)ammoniumbromid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(113)Suppliers

90-22-2, Valethamate bromide Verwandte Suche: