4-amidinoindan-1-one 2'-amidinohydrazone

4-amidinoindan-1-one 2'-amidinohydrazone Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM.

• in vitro

  Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC ₅₀ of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.

• target

  IC50: 5 nM (SAMDC)

4-amidinoindan-1-one 2'-amidinohydrazone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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