1-tert-Butoxy-N,N,N',N'-tetramethylmethylendiamin

Bezeichnung:1-tert-Butoxy-N,N,N',N'-tetramethylmethylendiamin

CAS-Nr5815-08-7

Englisch Name:tert-Butoxy bis(dimethylamino)methane

CBNumberCB0122973

SummenformelC9H22N2O

Molgewicht174.28

MOL-Datei5815-08-7.mol

Synonyma

1-tert-Butoxy-N,N,N',N'-tetramethylmethylendiamin

1-tert-Butoxy-N,N,N',N'-tetramethylmethylendiamin physikalisch-chemischer Eigenschaften

Siedepunkt	50-55 °C/15 mmHg (lit.)
Dichte	0.844 g/mL at 25 °C (lit.)
Brechungsindex	n20/D 1.422(lit.)
Flammpunkt	106 °F
storage temp.	Sealed in dry,Store in freezer, under -20°C
Löslichkeit	Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
pka	5.46±0.38(Predicted)
Aggregatzustand	Liquid
Farbe	Clear pale yellow
Wichte	0.844
BRN	1901973
Stabilität	Hygroscopic
InChI	InChI=1S/C9H22N2O/c1-9(2,3)12-8(10(4)5)11(6)7/h8H,1-7H3
InChIKey	HXRAMSFGUAOAJR-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(N(C)C)N(C)C
CAS Datenbank	5815-08-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi,F
R-Sätze:	10-36/37/38
S-Sätze:	26
RIDADR	UN 1993 3/PG 3
WGK Germany	3
F	10
HazardClass	3
PackingGroup	III
HS Code	29221990

Gefahreninformationscode (GHS)

tert-Butoxy bis(dimethylamino)methane Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R10:Entzündlich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Bredereck's reagent, chemically known as tert-Butoxy bis(dimethylamino)methane, is a versatile reagent. It can be used for a-methylation, a-methylenation, and a-amidation of multiple carbonyl systems or compounds with active CH groups. The advantage is the in situ generation of strongly basic alkanes (t-BuO-) and the generation of the corresponding iminium ions by thermal decomposition. After the Mannich reaction of the carbonyl substrate with the in situ generated iminium ion, the dimethylamine is eliminated from the adduct B- in the final step to give the condensation product, which can be converted into various types of compounds.
Chemische Eigenschaften
Clear pale yellow liquid
Verwenden
Reactant for:
- Preparation of pyrroloquinazolines as photochemotherapeutic agents
- Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition
- Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction
- Aminomethylenation reactions
Verwenden
Mild enamination reagent; catalyst in ring-opening polymerization reactions.
Verwenden
Reactant for:• ;Preparation of pyrroloquinazolines as photochemotherapeutic agents1• ;Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition2• ;Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction3• ;Aminomethylenation reactions4

tert-Butoxy bis(dimethylamino)methane Upstream-Materialien And Downstream Produkte

1-tert-Butoxy-N,N,N',N'-tetramethylmethylendiamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

5815-08-7, tert-Butoxy bis(dimethylamino)methane Verwandte Suche:

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