ChemicalBook CAS数据库列表 7,8-二氢-D-新蝶呤
7,8-二氢-D-新蝶呤
- CAS号:1218-98-0
- 英文名:7,8-DIHYDRONEOPTERIN
- 中文名:7,8-二氢-D-新蝶呤
- CBNumber:CB5479515
- 分子式:C9H13N5O4
- 分子量:255.23
- MOL File:1218-98-0.mol
7,8-二氢-D-新蝶呤化学性质
- 熔点 :>167°C (dec.)
- 沸点 :614.6±65.0 °C(Predicted)
- 密度 :2.03±0.1 g/cm3(Predicted)
- 储存条件 :−20°C
- 溶解度 :Aqueous Acid (Slightly), DMSO (Slightly)
- 形态 :Solid
- 酸度系数(pKa) :9.88±0.20(Predicted)
- 颜色 :Pale Yellow
- BRN :1133875
安全信息
7,8-二氢-D-新蝶呤性质、用途与生产工艺
- 生物活性 7,8-Dihydroneopterin 是一种炎症标记，通过增强一氧化氮合酶 (iNOS) 的表达来诱导星形胶质细胞和神经元细胞凋亡 (apoptosis)。可用于神经退行性疾病的研究。
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靶点
Apoptosis; iNOS
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体外研究
7,8-Dihydroneopterin is a heterocyclic pteridine which produced and secreted by monocytes/macrophages upon stimulation with the cytokine interferon-y (IFN-y).
7,8-Dihydroneopterin (0.1, 0.5, 1, 2.5, 5 mM; 2 days and 5 days) inhibits growth of U373MG astroeytes .Cell Viability Assay
Cell Line: Astrocytic cell line U373MG Concentration: 0.1, 0.5, 1, 2.5, 5 mM Incubation Time: 2 days and 5 days Result: After 2 days of treatment, a significantly lower cell number was observed for those cells treated with 5 mM and 2.5 mM.
After incubation for 5 days concentrations of 1-5 mM completely abrogated acid phosphatase activity to background level found for complete cell culture medium.
A significant cell growth inhibition was also visible for the cells incubated with 0.5 mM, whereas 0.1 mM did not alter cell growth.
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7,8-二氢-D-新蝶呤 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-136341
- 产品名称：7,8-二氢-D-新蝶呤 7,8-Dihydroneopterin
- CAS编号：
- 包装：1 mg
- 价格：600元
- 更新日期：2024/11/08
- 产品编号：HY-136341
- 产品名称：7,8-二氢-D-新蝶呤 7,8-Dihydroneopterin
- CAS编号：1218-98-0
- 包装：5mg
- 价格：1500元
7,8-二氢-D-新蝶呤生产厂家
- 公司名称：TORONTO
- 联系电话：--
- 电子邮件：info@trc-canada.com
- 国家：加拿大
- 产品数：6038
- 优势度：71
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