N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea化学性质

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea性质、用途与生产工艺

生物活性 N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide 是一种抗惊厥剂，有研究广泛强直和部分性发作挛性的潜质。
体内研究

Compound shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg. The activity seen with 30 mg/kg 37 is still present 4 h postdose. Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol. The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures. Compound is selected for clinical trials.

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea上下游产品信息

上游原料

下游产品

更新日期：2024/11/08
产品编号：HY-101708
产品名称：N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
CAS编号：
包装：5 mg
价格：1050元

更新日期：2024/11/08
产品编号：HY-101708
产品名称：N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
CAS编号：
包装：10 mM * 1 mLin DMSO
价格：1160元

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