94105-90-5
基本信息
(+)-雌马酚
R,S-雌马酚
纳米脂质体雌马酚
(卤)-EQUOL
雌马酚,(±)-雌马酚
雌马酚 98% 不是S型,混旋的
3-(4-羟基苯基)四氢苯并吡喃-7-醇
(+/-)Equol
(+/-)-EQUOL
Equol,99%e.e.
EQUOL(RACEMIC)
(+/-)-Equol>
(+/-)-Equol (GMP)
7,4'-HoMoisoflavane
(±)-EQUOL >= 99.0% (TLC)
4′,7-Dihydroxyisoflavane
物理化学性质
| 熔点 | 158-160?C |
| 沸点 | 441.7±45.0 °C(Predicted) |
| 密度 | 1.286±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C冷冻 |
| 溶解度 | 溶于乙醇 |
| 酸度系数(pKa) | 9.94±0.40(Predicted) |
| 形态 | 结晶粉末 |
| 颜色 | 白色至浅黄色至浅红色 |
| 水溶解性 | Soluble in DMSO and methanol or 100% ethanol. Insoluble in water. |
| 敏感性 | 吸湿性 |
| BRN | 87752 |
| InChI | InChI=1S/C15H14O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-6,8,12,16-17H,7,9H2 |
| InChIKey | ADFCQWZHKCXPAJ-UHFFFAOYSA-N |
| SMILES | C1OC2=CC(O)=CC=C2CC1C1=CC=C(O)C=C1 |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H302-H315-H319-H332-H335 |
| 防范说明 | P261-P280-P305+P351+P338 |
| WGK Germany | 3 |
| 海关编码 | 2932990090 |
雌马酚价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/05 | E0922 | (±)-雌马酚 (±)-Equol | 94105-90-5 | 200mg | 20元 |
常见问题列表
Equol is first isolated and identified from pregnant-mares' urine and later found in the urine of the goat, cow, hen and sheep. Equol, unlike the soy isoflavones daidzein or genistein, has a chiral center and therefore can occur as 2 distinct diastereoisomers. S-equol is the exclusive product of human intestinal bacterial synthesis from soy isoflavones and both enantiomers are bioavailable. S-equol has a high affinity for estrogen receptor beta (K i =0.73 nM), whereas R-equol is relatively inactive. Equol could promote the proliferation and differentiation of rat osteoblasts through activating the ER-PKCα-related signaling pathway. The alkaline phosphatase activity also increases significantly in all of the equol and 17β-estradiol (E2 ) groups. Equol also significantly elevates the osteocalcin levels.
Equol is a modest natriuretic and vasorelaxant agent in the rat. Orally administered equol is about 8-fold less potent than orally administered furosemide. In isolated aortic rings precontracted by administration of phenylephrine, administration of equol relaxes the contracted aorta (concentration for half-maximal activity 58.9±16 μM). Equol possesses anticancer activity that suppresses tumor formation via apoptosis induction in rats with DMBA-induced mammary gland tumors. In addition, equol shows a hepatic protective effect by acting as an antioxidant and by reducing apoptosis.