774551-07-4
英文名称
2-[2-chloro-4-({[2-(1H-indol-3-yl)ethyl]amino}methyl)-6-methoxyphenoxy]acetamide
CAS
774551-07-4
分子式
C20H22ClN3O3
分子量
387.86
MOL 文件
774551-07-4.mol
结构式
基本信息
英文别名
M75940037
M7594-0037
M7594_0037
M7594 0037
2-[2-chloro-4-({[2-(1H-indol-3-yl)ethyl]amino}methyl)-6-methoxyphenoxy]acetamide
M7594-0037
M7594_0037
M7594 0037
2-[2-chloro-4-({[2-(1H-indol-3-yl)ethyl]amino}methyl)-6-methoxyphenoxy]acetamide
应用领域
用途一
M7594_0037 is a small molecule inhibitor of human peptide deformylase (HsPDF). HsPDF is an important target for anticancer drug discovery. M7594_0037 exhibits potent anticancer activities against HeLa, A549 and MCF-7 cell lines with IC50s of 35.26, 29.63 and 24.63 μM, respectively.