603101-22-0
中文名称
GNF1331
英文名称
GNF1331
CAS
603101-22-0
分子式
C20H20N6O2S2
分子量
440.54
MOL 文件
603101-22-0.mol
结构式
物理化学性质
| 密度 | 1.44±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 8.68±0.70(Predicted) |
| 形态 | Solid |
| 颜色 | Yellow to brown |
应用领域
用途一
GNF-1331 is a Potent, Selective, and Orally Bioavailable Porcupine Inhibitor (IC50 = 12 nM). Blockade of aberrant Wnt signaling is an attractive therapeutic approach in multiple cancers. Wnt signaling is tightly controlled during cellular proliferation, differentiation, and embryonic morphogenesis. Aberrant activation of this pathway plays a critical role in a variety of cancers, such as cutaneous squamous cell carcinoma (SCC), breast cancer, and colorectal cancer.
供应商信息 更多
TargetMol中国（陶术生物）
联系电话：
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产品介绍：
中文名称：化合物 GNF-1331
英文名称：GNF-1331
CAS：603101-22-0
包装信息：25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800