264275-77-6
中文名称
L-ALANINE, N-[2,6-DICHLORO-4-[[[(3-HYDROXYPHENYL)METHYL]AMINO]CARBONYL]BENZOYL]-3-[(3,5-DIHYDROXYBEN
英文名称
L-Alanine, N-[2,6-dichloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3,5-dihydroxybenzoyl)amino]-
CAS
264275-77-6
分子式
C25H21Cl2N3O8
分子量
562.36
MOL 文件
264275-77-6.mol
结构式
基本信息
中文别名
L-ALANINE, N-[2,6-DICHLORO-4-[[[(3-HYDROXYPHENYL)METHYL]AMINO]CARBONYL]BENZOYL]-3-[(3,5-DIHYDROXYBEN
英文别名
XVA143
L-Alanine, N-[2,6-dichloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3,5-dihydroxybenzoyl)amino]-
L-Alanine, N-[2,6-dichloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3,5-dihydroxybenzoyl)amino]-
应用领域
用途一
XVA143 is a α/β I allosteric inhibitor of the integrin leucocyte function-associated antigen-1 (αLβ2, LFA-1) which plays crucial roles in T cell adhesion, migration and immunological synapse (IS) formation. Consequently, αLβ2 is an important therapeutic target in autoimmunity.