2390367-27-6
中文名称
CPI-1328
英文名称
1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one, 9-chloro-6-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(dimethylamino)cyclohexyl]-7,8-dihydro-2,4-dimethyl-, (2R)-
CAS
2390367-27-6
分子式
C28H36ClN3O4S
分子量
546.12
MOL 文件
2390367-27-6.mol
结构式
基本信息
中文别名
英文别名
CPI-1328
1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one, 9-chloro-6-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(dimethylamino)cyclohexyl]-7,8-dihydro-2,4-dimethyl-, (2R)-
1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one, 9-chloro-6-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(dimethylamino)cyclohexyl]-7,8-dihydro-2,4-dimethyl-, (2R)-
物理化学性质
| 沸点 | 738.0±60.0 °C(Predicted) |
| 密度 | 1.33±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 10.89±0.10(Predicted) |
应用领域
用途一
CPI-1328 is a highly potent second-generation EZH2 inhibitor with extended residence times and improved biological activity.
常见问题列表
概述
CPI-1328 是一种 EZH2 抑制剂，其 Ki 值为 63 fM。