2127150-20-1
英文名称
JANELIA FLUOR 669, SE
CAS
2127150-20-1
分子式
C34H30F3N3O6SSi
分子量
693.77
MOL 文件
2127150-20-1.mol
结构式
基本信息
英文别名
JF669, SE
JANELIA FLUOR 669, SE
1-[7-(1-Azetidinyl)-10-[2-Carboxy-5-[(2-(2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl]thio-3,4,6-trifluorophenyl]-9,9-dimethyl-9-silaanthracen-2(9H)-ylidene]azetidinium, inner salt
JANELIA FLUOR 669, SE
1-[7-(1-Azetidinyl)-10-[2-Carboxy-5-[(2-(2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl]thio-3,4,6-trifluorophenyl]-9,9-dimethyl-9-silaanthracen-2(9H)-ylidene]azetidinium, inner salt
物理化学性质
| 溶解度 | Soluble to 20 mM in DMSO |
| 形态 | Solid |
| 颜色 | Light green to green |
常见问题列表
生物活性
JF669, SE 是一种红色的荧光染料，可与含巯基的卤代标记配体在温和的条件下 (DIEA, DMF) 反应，一步形成 JF669−HaloTag (Ex = 669 nm; Em = 682 nm)。
体外研究
JF669 undergoes rapid conversion to thioether product (<5 min to completion) in organic solvents, where the dye predominantly adopts the closed form. JF669 displays comparatively excellent photostability, retaining 97% fluorescence after the same number of cycles.