1950647-99-0
中文名称
PROPANOIC ACID, 2,2-DIMETHYL-, 1,1′,1′′,1′′′-[[2-(2-THIAZOLYLAMINO)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS
英文名称
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester
CAS
1950647-99-0
分子式
C29H50N2O14P2S
分子量
744.73
MOL 文件
1950647-99-0.mol
结构式
基本信息
中文别名
PROPANOIC ACID, 2,2-DIMETHYL-, 1,1′,1′′,1′′′-[[2-(2-THIAZOLYLAMINO)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS
英文别名
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester
应用领域
用途一
HUN47990 is a bisphosphonate (BP) prodrug with antitumor activity. HUN47990 potently inhibits the in vitro growth of a variety of tumor cell lines, especially hematopoietic cell lines, at nanomolar concentrations. HUN47990 inhibited the prenylation of the RAP1A small GTPase signaling protein at concentrations as low as 1-10 nM. HUN47990 slowed the growth of human bladder cancer cells in an immunodeficient mouse model. HUN47990 is significantly more active than zoledronic acid, the most active FDA-approved BP, and a potential anti-cancer therapeutic. HUN47990 was first reported in ChemMedChem. 2016 Dec 16;11(24):2656-2663 (compound 7). This product has no formal name at the moment.
供应商信息 更多
江苏药泽医药科技有限公司
联系电话：
18962082606
产品介绍：
英文名称：Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester
CAS：1950647-99-0
纯度：95%
包装信息：1g/;5g/
TargetMol中国（陶术生物）
联系电话：
15002134094
产品介绍：
中文名称：化合物 HUN47990
英文名称：HUN47990
CAS：1950647-99-0
包装信息：100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800