17511-50-1
中文名称
3-[(4-苄基-1-哌嗪基)甲基]吲哚
英文名称
UA8967
CAS
17511-50-1
分子式
C20H23N3
分子量
305.42
MOL 文件
17511-50-1.mol
结构式
基本信息
中文别名
3-[(4-苄基-1-哌嗪基)甲基]吲哚
英文别名
UA8967
3-[(4-Benzyl-1-piperazinyl)methyl]indole
3-[(4-benzylpiperazin-1-yl)methyl]-1H-indole
3-[(4-Benzyl-1-piperazinyl)methyl]indole
3-[(4-benzylpiperazin-1-yl)methyl]-1H-indole
应用领域
用途一
UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 12–61 μM for exposure times of 72 h. There was also no selective inhibition of DNA, RNA or protein synthesis after exposure to UA8967. UA8967 is observed to affect the plasma membrane.