167006-13-5
中文名称
化合物 T27743
英文名称
1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-
CAS
167006-13-5
分子式
C25H23N7O3S
分子量
501.56
MOL 文件
167006-13-5.mol
结构式
基本信息
中文别名
化合物 T27743
英文别名
WK1492
WK-1492
WK14922K
WK-14922K
KRH-594 free acid
1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-
WK-1492
WK14922K
WK-14922K
KRH-594 free acid
1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-
应用领域
用途一
KRH-594, also known as WK-1492; WK-14922K, is a potent, specific and insurmountable AT1 receptor antagonist. KRH-594 prevents end-organ damage in stroke-prone spontaneously hypertensive/Izm rats. KRH-594 ameliorates nephropathy and hyperlipidaemia in diabetic spontaneously hypertensive rats.