146935-36-6

Dactylfungin B is isolated from Dactylaria parvispora. Dactylfungins are novel antifungal antibiotics produced by Dactylaria parvispora. Novel antifungal antibiotics, designated as dactylfungins A (1) and B (3), were isolated from the culture broth of Dactylaria parvispora D500. Dactylfungins A and B were found to be new substances containing an alpha-pyrone and a gamma-pyrone ring, respectively, which conjoined with a polyalcohol moiety and a long side chain, based on NMR spectral analyses. The antibiotics were active against Candida pseudotropicalis and other fungi, with an MIC value at less than 10 micrograms/ml.

Dactylfungin B (MK 2266 B) 是一种抗真菌抗生素 (antibiotic)，可有效对抗假热带念珠菌和其他真菌，MIC 值为 <10 μg/mL。