1361415-84-0
英文名称
AC410
CAS
1361415-84-0
分子式
C19H16FN5O
分子量
349.362
MOL 文件
1361415-84-0.mol
结构式
基本信息
英文别名
AC410
应用领域
用途一
AC410 is a potent, selective, orally-administered, small molecule inhibitor of Janus kinase 2 (JAK2, Kd = 0.18 nM) and has potential utility in autoimmune and inflammatory indications. Activity data: the specificity of AC410 for JAK2 vis-a-vis JAK1 (Kd = 2.5 nM) and JAK3 (Kd = 5 nM).