117978-26-4
中文名称
A 62198
英文名称
A 62198
CAS
117978-26-4
分子式
C30H44N8O5
分子量
596.72
MOL 文件
117978-26-4.mol
结构式
基本信息
中文别名
化合物 T26426
英文别名
A 62198
Reaxys ID: 26144718
5-Azido-1-cyclohexyl-1,2,5-trideoxy-2-[[N-[N-(2-methyl-1-oxopropyl)-L-phenylalanyl]-L-histidyl]amino]-L-arabino-pentitol
N-[1-[[1-[(5-azido-1-cyclohexyl-3,4-dihydroxy-pentan-2-yl)carbamoyl]-2-(3H-imidazol-4-yl)ethyl]carbamoyl]-2-phenyl-ethyl]-2-methyl-propanamide
Reaxys ID: 26144718
5-Azido-1-cyclohexyl-1,2,5-trideoxy-2-[[N-[N-(2-methyl-1-oxopropyl)-L-phenylalanyl]-L-histidyl]amino]-L-arabino-pentitol
N-[1-[[1-[(5-azido-1-cyclohexyl-3,4-dihydroxy-pentan-2-yl)carbamoyl]-2-(3H-imidazol-4-yl)ethyl]carbamoyl]-2-phenyl-ethyl]-2-methyl-propanamide
物理化学性质
| 酸度系数(pKa) | 13.183±0.20(predicted) |
应用领域
用途一
A 62198 is a potent and selective renin inhibitor. A-62198 induced a dose-dependent fall in mean arterial blood pressure (MAP) when administered as an i.v. bolus to anesthetized, salt-depleted monkeys. It has potential as a hypotensive agent.
供应商信息 更多
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产品介绍：
中文名称：化合物 A 62198
英文名称：A 62198
CAS：117978-26-4
包装信息：100mg/RMB 23500;50mg/RMB 18300;25mg/RMB 13900