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Methyl 5-((tert-butoxycarbonylamino)methyl)-2-chlorobenzoate (100 mg, 0.334 mmol) was used as a raw material, which was dissolved in 1 mL of EtOAc solution saturated with HCl and the reaction was stirred for 2 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated and ground with pentane to yield 80 mg of the final target product, methyl 5-(aminomethyl)-2-chlorobenzoate hydrochloride. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 8.20 (br s, 3H), 7.95 (s, 1H), 7.67 (s, 2H), 4.00 (s, 2H), 3.88 (s, 3H).

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