899947-07-0

STING-IN-7 (compound 21) is a potent STING inhibitor with an IC50 of 11.5 nM. STING-IN-7 inhibits the phosphorylation of STING and interferon regulatory factor 3 (IRF3)[1].

[1] Po-Wei Chang, et al. Analysis of structure-activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors. Bioorg Med Chem. 2023 Oct 14:95:117502. DOI:10.1016/j.bmc.2023.117502