85797-13-3

Name	(+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC
CAS	85797-13-3
Molecular Formula	C7H16NO5P
MDL Number	MFCD00055057
Molecular Weight	225.18
MOL File	85797-13-3.mol

Synonyms

Brn 3544152 2-amino-7-phosphono-heptanoicaci (+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC Heptanoic acid, 2-amino-7-phosphono-

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Safety Data

Safety Statements	22-24/25 less more
RTECS	MJ1927500

Hazard Information

Uses

DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1].

in vivo

DL-AP7 (ICV) blocks the NMDA-induced convulsions (ED₅₀=0.22 nmol/mouse) and impairs learning performance in a passive avoidance task in mice^[1].

IC 50

NMDA Receptor

References

[1] Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl). 1990;102(4):551-552. DOI:10.1007/BF02247140

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