Uses
This allylboration reagent is a convenient, salt-free, stable solution of a chiral allyl borane for asymmetric allylation of aldehydes leading to chiral homoallylic alcohols.
Preparation
(-)-IPC2B(ALLYL), 1M IN PENTANE can be prepared in three steps from either (+)- or (-)-α-pinene (eq 1) .
Reactions
(-)-IPC2B(ALLYL), 1M IN PENTANE is most often used as the crude preparation in Et2O; however, reactions have also been conducted in CS2, CHCl3, CH2Cl2, toluene, and THF.
Solubility in organics
(-)-IPC2B(ALLYL), 1M IN PENTANE is most often used as the crude preparation in Et2O; however, reactions have also been conducted in CS2, CHCl3, CH2Cl2, toluene, and THF.
