ChemicalBook CAS DataBase List 84878-61-5

84878-61-5

Name	Maduramycin ammonium
CAS	84878-61-5
EINECS(EC#)	635-502-4
Molecular Formula	C47H83NO17
MDL Number	MFCD08273836
Molecular Weight	934.16
MOL File	84878-61-5.mol

Synonyms

Cygro Maduramicin princin ammonoum Prinicin ammonium Maduraminic Ammonium MADURAMYCIN AMMONIUM MADURAMICIN AMMONIUM Madubamycin ammonium Maduramincin ammonium maduramicin ammonoium MADURAMICIN AMMONIUM SALT MADURAMICIN AMMONIUM 90% Maduramicin ammonium premix maduramycin ammonium premix MaduraMycin 1% HOUSE STANDARD CL 259971, MaduraMycin sodiuM Maduramicin a, Monoammonium Salt MaduraMicin α, MonoaMMoniuM Salt Decocci (Maduramcin ammonium premix) 2H-Pyran-2-acetic acid, 6-(1R)-1-(2S,5R,7S,8R,9S)-2-(2S,2R,3S,5R,5R)-3-(2,6-dideoxy-3,4-di-O-methyl-.beta.-L-arabino-hexopyranosyl)oxyoctahydro-2-methyl-5-(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl2,2-bifuran-5-yl-9-hydroxy-2,8-dimet (2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-3'-[(2,6-Dideoxy-3,4-di-O-methyl-b-L-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5'-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]tetrahydro-2-hydroxy-4,5-dimethoxy-3-methyl-2H-pyran-2-acetic acid monoammonium salt (2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-3'-[(2,6-Dideoxy-3,4-di-O-methyl-b-L-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5'-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]tetrahydro-2-hydroxy-4,5-dimethoxy-3-methyl-2H-pyran-2-acetic acid monoammonium salt

Chemical Properties

Melting point	173-176 °C
storage temp.	0-6°C
solubility	DMF: 1 mg/ml
form	neat
color	White to light yellow

Safety Data

Hazard Codes	T+
Risk Statements	25-27-36 less more
Safety Statements	26-28-36/37-45 less more
RIDADR	UN 2811
WGK Germany	3
HazardClass	6.1
PackingGroup	III

Hazard Information

Chemical Properties

White Solid

Usage

Maduramcin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.

Usage

Maduramicin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.

Usage

Polyether antibiotic chemically related to the lonomycins. Coccidiostat

Uses

Polyether antibiotic chemically related to the lonomycins. Coccidiostat

Definition

ChEBI: Maduramicin is a glycoside.

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