General Description
White crystalline solid. Sinks and mixes with water.
Reactivity Profile
STANNOUS FLUORIDE(7783-47-3), a strong reducing agent, is incompatible with oxidizers. Avoid contact with acids-HF fumes may be produced [USCG, 1999].
Air & Water Reactions
Water soluble.
Health Hazard
EYES: Severe irritation-corrosive, irreversible. SKIN: Corrosive on abraded skin, no effect on intact skin.
Potential Exposure
Stannous fluoride is used in dental caries (tooth decay); as an ingredient of cavity-preventing toothpastes.
First aid
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. For heated stannous fluoride exposure medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy. If swallowed, watch for symptoms of shock.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2923 Corrosive solids, toxic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, 6.1Poisonous material, Technical Name Required
Incompatibilities
A strong reducing agent. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Reacts with acids, forming hydrogen fluoride fumes. Reacts violently with chlorine and metal nitrates. Reacts with metals releasing flammable hydrogen gas.
Chemical Properties
Stannous fluoride is a white crystalline solid with a bitter, salty taste.
Chemical Properties
white crystals or powder
Uses
Dental caries prophylactic.
Uses
Stannous fluoride (SnF2) is used as a toothpaste additive to help prevent tooth decay.
Definition
ChEBI: Stannous fluoride is an inorganic fluoride salt.
Hazard
Toxic by ingestion, strong irritant to skin
and tissue.
Flammability and Explosibility
Notclassified
reaction suitability
core: tin
reagent type: catalyst
Biological Activity
The wild type human brahma-related gene 1 (Brg1) encodes a protein of 1,647 amino acids th at contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription regulation. BRG1 is an essential component of the SWI/SNF chromatin remodeling complexes and implicated in multiple functions through its interaction with different proteinsincluding the tumor suppressor protein pRbserine-threonine kinase LKB1and other transcription factors. Although Brg1 is involved in chromatin remodeling as a complex with other SWI/SNF proteinspurified BRG1 itself is capable of remodeling mono-nucleosomes and nucleosomal arrays in vitro. Mutations of Brg1 have been found in multiple tumor cell lines.
