ChemicalBook CAS DataBase List 7446-18-6

7446-18-6

Name	THALLIUM(I) SULFATE
CAS	7446-18-6
EINECS(EC#)	231-201-3
Molecular Formula	O4STl2
MDL Number	MFCD00011278
Molecular Weight	504.83
MOL File	7446-18-6.mol

Chemical Properties

Appearance	white fine crystalline powder or needles
Melting point	632 °C(lit.)
Boiling point	decomposes [STR93]
density	6.77 g/mL at 25 °C(lit.)
refractive index	1.860
storage temp.	Poison room
solubility	Water (Slightly)
form	Crystals or Powder
color	White to off-white
Specific Gravity	6.77
Water Solubility	Solubility in water increases with temperatureSoluble in water.
Merck	14,9269
InChI	1S/H2O4S.2Tl/c1-5(2,3)4;;/h(H2,1,2,3,4);;/q;2*+1/p-2
InChIKey	YTQVHRVITVLIRD-UHFFFAOYSA-L
SMILES	[Tl+].[Tl+].[O-]S([O-])(=O)=O
CAS DataBase Reference	7446-18-6(CAS DataBase Reference)
EPA Substance Registry System	Thallium(I) sulfate (7446-18-6)

Safety Data

Hazard Codes	T+,N
Risk Statements	R28:Very Toxic if swallowed. R38:Irritating to the skin. R48/25:Toxic: danger of serious damage to health by prolonged exposure if swallowed . R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . less more
Safety Statements	S13:Keep away from food, drink and animal feeding stuffs . S36/37:Wear suitable protective clothing and gloves . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S61:Avoid release to the environment. Refer to special instructions safety data sheet . less more
RIDADR	UN 1707 6.1/PG 2
WGK Germany	2
RTECS	XG6800000
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	28332980
Storage Class	6.1B - Non-combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 2 Oral Acute Tox. 3 Dermal Aquatic Acute 1 Aquatic Chronic 2 Skin Irrit. 2 STOT RE 1 Oral
Safety Profile	Human poison by ingestion. Experimental poison by ingestion and subcutaneous routes. Human systemic effects by ingestion: ataxia, change in heart rate, excitement, eye changes, irritability, nausea or vomiting, nerve or sheath structural changes, somnolence, wakefulness. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of T1 and SOx. Used as a rat poison, ant bait, and a reagent in analytical chemistry. See also THALLIUM COMPOUNDS and SULFATES. less more
Hazardous Substances Data	7446-18-6(Hazardous Substances Data)
Toxicity	LD50 orally in rats: 25 mg/kg, E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972) less more

Raw materials And Preparation Products

Hazard Information

Chemical Properties

white fine crystalline powder or needles

Uses

As rat poison, as ant bait and as a reagent in analytical chemistry.

General Description

Odorless white rhomboid prisms or a dense white powder. Density 6.77 g/cm3. Melting point 1170°F (632°C). Extremely toxic by ingestion. Very toxic by skin absorption and ingestion. A slow acting cumulative poison. Used as a rat poison, and an ant bait. Also used for analysis (testing for iodine in the presence of chlorine) and ozonometry. Not registered as a pesticide in the U.S.

Reactivity Profile

THALLIUM SULFATE(7446-18-6) has weak oxidizing and weak reducing powers. Redox reactions can however still occur.

Air & Water Reactions

Soluble in water.

Health Hazard

Rated as extremely toxic. The probable oral lethal dose in humans is 5 to 50 mg/kg, or between 7 drops and 1 teaspoon for a 150-pound person. The mean lethal dose in an adult is probably about 1 gm of thallium sulfate. Chronic exposure causes hair loss starting 10 days after exposure and complete baldness in about a month.

Fire Hazard

When heated to decomposition, THALLIUM SULFATE emits very toxic fumes of thallium and sulfur oxide.

Definition

ChEBI: Thallium sulfate is a metal sulfate in which the counterion is thallium and the ratio of thallium to sulfate is 2:1. It is a rodenticide used to control rats, squirrels, mice, moles, prairie dogs, ants and cockroaches. It is no longer registered for pesticide use in the United States. It has a role as a rodenticide and an insecticide. It is a thallium molecular entity and a metal sulfate. It contains a thallium(1+) and a sulfate.

Production Methods

Commercial sources are flue dusts, either from pyrite (FeS2) burners or from lead and zinc smelters and refiners, as a byproduct of cadmium production at the rate of a few thousand pounds per year. In the flue dusts thallium occurs largely as a sulfate, which is extracted with hot water or dilute sulfuric acid. The purification of thallium is accomplished by taking advantage of the difference in solubility of certain thallium compounds and the impurities. Traces of zinc, copper, cadmium, lead, and indium are removed by dissolving the thallium in and precipitating the impurities with hydrogen sulfide.

Purification Methods

The sulfate crystallises from hot water (7mL/g) by cooling; then dry it under vacuum over P2O5. It is POISONOUS.

Mechanism of action

Disrupts essential cellular processes including pyruvate kinase and succinate dehydrogenase

Carcinogenicity

Thallium is not classifiable with respect to carcinogenicity due to a lack of relevant human and animal studies. Several subchronic and chronic animal studies on thallium and compounds are available; however, they were not designed to examine carcinogenic end points.

7446-18-6

Chemical Properties

Safety Data

Raw materials And Preparation Products

Preparation Products

Hazard Information

Chemical Properties

Uses

General Description

Reactivity Profile

Air & Water Reactions

Health Hazard

Fire Hazard

Definition

Production Methods

Purification Methods

Mechanism of action

Carcinogenicity

Pesticide Type

Material Safety Data Sheet(MSDS)

Spectrum Detail

Well-known Reagent Company Product Information