741-58-2

Colorless liquid; slight odor.Insoluble in water; soluble in kerosene and xylene.

Highly toxic, cholinesterase inhibitor. Use may be restricted.

A selective preemergence organophosphate herbicide used to control bluegrass, crabgrass and other annual grasses and broadleaf weed s in agriculture crops, cotton and turf. It is widely used on golf courses and home lawns. Target weeds also include barnyard grass, burning nettle, and canary grass.

Treatment for organophosphate poisoning consists of thorough decontamination, cardiorespiratory support, and administration of the antidotes atropine and pralidoxime. In cases of severe poisoning, diazepam, an anticonvulsant, should also be administered. Antidotes should be administered as prevention even if the diagnosis is in doubt. Speed in removing material from eyes and skin is of extreme importance. Eyes: Eye contact can cause dangerous amounts of these chemicals to be quickly absorbed through the mucous membrane into the bloodstream. Immediately and gently flush eyes with plenty of warm or cold water (NO hot water) for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Dermal contact can cause dangerous amounts of these chemicals to be absorbed into the bloodstream. Wearing the appropriate PPE equipment and respirator for organophosphate/carbamate pesticides, immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Shampoo hair promptly if contaminated. The removed, contaminated clothing and shoes should be double-bagged and left in Hot Zone for later disposal by hazardous materials experts. Skin may also be decontaminated with diluted hypochlorite solution. Inhalation: Get medical aid. Do not contaminate yourself. Wearing the appropriate PPE equipment and respirator for organophosphate pesticides, immediately remove the victim from the contaminated area to fresh air. If the victim is not breathing, administer artificial respiration. Do not use mouth-tomouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If breathing is difficult, administer oxygen through bag/mask apparatus until medical help arrives. Do not leave victim unattended. Ingestion: Call poison control. Loosen all clothing. Never give anything by mouth to an unconscious person. If victim is unconscious or having convulsions, do nothing except keep victim warm. Get medical aid. Transfer promptly to a medical facility. In cases of ingestion, do not induce vomiting. If the victim is alert and asymptomatic, administer a slurry of activated charcoal at a dose of 1 g/kg (infant, child, and adult dose). A soda can and straw may be of assistance when offering charcoal to a child. In some cases you may be specifically instructed by poison control to induce vomiting by way of 2 tablespoons of syrup of ipecac (adult) washed down with a cup of water. Do NOT give activated charcoal before or with ipecac syrup.

UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9—Miscellaneous hazardous material, Technical Name Required.

Incompatible with oxidizers; chlorates nitrates, peroxides. Decomposes slowly in light and strong UV. Corrosive to copper, aluminum, magnesium, zinc. Slowly hydrolyzes in water, releasing ammonia gas and forming acetate salts. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas. Contact with oxidizers can cause the release of toxic oxides of phosphorus. Stable @ 80 C for 50 hours; decomposes @ 200° C in 18 40 hours.

Destruction by alkali hydrolysis or incineration. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

ChEBI:Bensulide is a member of benzenes.

Herbicide: A selective pre-emergence herbicide used to control bluegrass, crabgrass and other annual grasses and broadleaf weeds in agriculture crops, cotton and turf. It is widely used on golf courses and home lawns. Target weeds also include barnyardgrass, burning nettle and canarygrass. Not approved for use in EU countries.

BENSUMEC®; BETAMEC®; BETASAN®; BETASAN®-E; BETASAN®-G; DISAN®; EXPORSAN®; KAYAPHENONE®; PREFAR®; PREFAR®-E; PRESAN ®; PROTURF®; R-4461®; SAP (herbicide)

Bensulide was given in the diet for 104 weeks to rats at levels to achieve doses of 0, 1, 15, or 60 mg/kg/day . No cholinergic signs were observed at any dose. Increased absolute liver weights accompanied by mild histopathological changes (hepatocyte vacuolation and eosinophilic foci) occurred at 60 mg/kg/day, but there was no evidence of carcinogenic potential.
Bensulide was given in the diet for 78 weeks to mice at levels to achieve 0, 1, 50, or 200 mg/kg/day . Survival rates, clinical observations, and hematological parameters were unaffected at all doses. Decreased overall body weight gains, increased absolute and relative liver weights accompanied by histopathological changes (pale foci, cell atypia, and cell foci) occurred at 200 mg/kg/day (males only). Overall body weight gain was also reduced in males at 50 mg/kg/day, but there was no evidence of carcinogenic potential.