Nicousamide is a potent inhibitor of TGF-β RII phosphorylation. Nicousamide can be used to study renal fibrosis in animal models of diabetic nephropathy[1].
References
[1] Zhang H, et al. Nicousamide, a potent inhibitor of phosphorylation by TGF-β receptor II. Acta Pharmaceutica Sinica B, 2011, 1(3): 160-165.
