Description
MD 770222 is a metabolite of cimoxatone that inhibits the deamination of noradrenaline.
Uses
MD 770222, a major plasma O-demethyl metabolite of Cimoxatone (HY-15386), is an orally active, selective and reversible MAO A inhibitor. MD 770222 shows less potent than Cimoxatone[1].
References
[1] V Rovei, et al. Pharmacokinetic and relative bioavailability studies of cimoxatone in humans. Int J Clin Pharmacol Ther Toxicol. 1984 Jan;22(1):56-62. PMID:6698662
